ABSTRACT
Aim: The study was carried out with an aim to evaluate an association of serum lipid profile with breast carcinoma and benign breast disease. Methods: For this purpose, a case-control study was planned in which a total of 105 subjects were enrolled according to a purposive sampling design - A total of 35 (33.3%) patients in each group having breast carcinoma, benign breast disease, and healthy controls were included for assessment. Lipid levels were assessed. Data were analyzed. Results: Age of subjects enrolled in the study ranged from 16 to 58 years. The mean age of subjects in malignant, benign and control group was 45.71 ± 10.04, 24.91 ± 6.83 and 35.60 ± 12.42 years, respectively. The majority of malignant cases were in advanced stage (T3 and T4), together accounted for 94.29% of total malignant cases. The remaining 2 (5.7%) cases were in T2-stage. A total of 21 (60%) cases had metastasis too. Mean triglyceride (TG) levels of malignant cases were significantly higher as compared to that of benign and healthy controls. Mean serum high density lipoproteins levels were significantly higher in benign group as compared to healthy controls. Mean serum low density lipoproteins levels were maximum in healthy controls and minimum in benign breast disease group. Statistically, the difference between healthy controls and benign breast disease was also found to be significant. Conclusion: For different lipid components, the relationship with different types of breast lesions was found to be varying. In malignant cases, TG levels showed an increased trend. The possibility of these relationships being random cannot be ignored. A larger study on larger sample size is recommended.
ABSTRACT
Background: Burn trauma is the common problems seen in emergency in tertiary care centre of Rohilkhand region. So, far there is no published study regarding the magnitude of burn trauma in this area. Aims & Objective: To study the etiology of major burn trauma in Rohilkhand region of Uttar Pradesh. Material and Methods: This retrospective study was carried out on 96 patients admitted in the Department of Surgery, Rohilkhand Medical College & Hospital, Bareilly during the period of 1st January 2010 to 31st December 2012. Results: Among the total of 36 patients (37.5%) from urban area, 16 (16.6%) were males and 20 (20.8%) were females and from rural area 46 (47.9%) were male and 14 (14.6) were female. The most frequent etiological agent was hot liquid (45.8%) followed by flame burns (33.3%), chemical (13.5%) and electrical (7.2%). Out of the total patients, 47 (48.9%) had 1 and 2 degree burn, 32 (33.3%) had 3 degree burn and 17 (17.7%) had mixed burn. Out of the total of 20 patients, who had died 6 were males and 14 were females. Conclusion: The most frequent cause of burn in Rohilkhand region was hot liquid. The mortality rate was higher for females than males.